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PI: Diego di Bernardo
@diegodibi.bsky.social (BlueSky)
Combining Molecular Biology, Computer Science and Biomedical Engineering to combat diseases
Combining Molecular Biology, Computer Science and Biomedical Engineering to combat diseases
Our lab combines Biology, Biomedical and Automation Engineering, and Computer Science with state-of-the-art approaches to develop innovative technologies to observe, model and program cell behaviour to advance basic and translational research in rare genetic disorders.
Systems Biology
Systems Biology
Our research aims at developing and applying experimental protocols and computational approaches to measure transcriptional responses of cells to perturbations to elucidate mechanisms of genetic diseases and for drug repurposing.
Synthetic Biology
Synthetic Biology
Synthetic Biology aims at rational engineering of living organisms. The overarching goal of the lab is to improve human well-being by engineering mammalian cells for biotechnological and biomedical applications. To do so, we are translating principles of control engineering in synthetic biology to engineer biomoleculer circuits to solve current challenges in the therapy of rare genetic disorders.
The lab has coordinated the H2020 FET OPEN EU project "COSY-BIO" The COSY-BIO Project — Cosy-Bio
NEWS
NEWS
Our lab is now funded by a prestigious ERC Advanced Grant of €2.5 million over five years for the project DIMERCIRCUITS. The goal: to design synthetic genetic circuits that can dynamically, precisely, and reversibly control gene expression — enabling safer and more personalized gene therapies. We are hiring PostDocs!!! If interested drop an email to Diego di Bernardo (dibernardo_at_tigem_dot_it)
A short Podcast explaining how CRISPRaic works!
Our Lab is supported by:
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