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    Gennaro Gambardella - Graduate Student


    Name: Gennaro

    Surname: Gambardella

    City and Birth: Napoli,May 18th, 1982

    Computer Skills

    Programming Language: C, C++, Java, MATLAB, Prolog, Pascal, and SQL.

    Web Applications: Java Servlets, JSP, HTML, XML, JDOM and PHP.

    Database: ORACLE, MySQL and PostgreSQL.



    2010-2013: PhD degree in Computational Biology and Bioinformatics (University of Naples, Federico II). Internship at the Telethon Institute of Genetics and Medicine (TIGEM) with Dr. Diego di Bernardo. Obtained on May 17th (2013). Title of thesis “Identification of transcriptional and post-translational regulatory networks from gene expression profiles: an information-theoretic approach.”

    2008-2009: M.Sc. degree in Computer Science, 110/110. Internship at the Telethon Institute of Genetics and Medicine (TIGEM) where I worked on the development of a method for the study and analysis of microarray experimental data from human and mouse tissues and cell types. The aim was the discovering tissue and cell specific gene regulation via a novel a data “warehousing” technique. The thesis was developed under the supervision Professor Adriano Peron and in collaboration with Diego di Bernardo at the Telethon Institute of Genetics and Medicine. Title of thesis: “Una piattaforma per lo studio e l'analisi di dati sperimentali della cellula e delle sue reti genetiche.”

    2005-2006: B.Sc. degree in Computer Science, 103/110 (Laurea I livello - 3 years University studies, Federico II, Naples). Internship at the Institute of Cybernetics "Eduardo Caianiello" at the C.N.R. Pozzuoli where I worked with Professor Francesco Mele for the preparation of my final year thesis. During my training I became competent in data resource integration with heterogeneous sources. Title of thesis: “Progetto S.I.Re.Na., integrazione di risorse per i Quartieri Spagnoli: un' interfaccia di accesso alle risorse”.

    1996-2001: I.T.I.S. “F. Giordani”, graduate with 74/100


    Research Experience

    2013 (April 22-23): Lecture at EPIGEN course: Introduction to reverse-engineering methods.

    2012 (April-May): Internship at the Sheffield University with Dr. Neill Lowrence for the development of new reverse-engineering strategy of post-translational interactions.

    2012 (November): Selected for poster presentation at RECOMB/DREAM 2012. “Identification of Post-Translational modifications from gene expression profiles using Multi-Information”. (G. Gambardella, N. Lawrence N. and D. di Bernardo).

    2011 (July): Invited as Tutors for Lifelong Learning Programme Erasmus - Interdisciplinary Approaches to Microarray Data Analysis. (Lab activity: Using reverse-engineered networks to understand gene function, drug mode of action and for gene signature analysis).

    2011 (September): Selected for poster presentation at ICSB 2011. Abstract title: "Identification of Active Metabolic Pathways and their Regulators from Differential Network Analysis (DINA)". (G. Gambardella and D. di Bernardo).

    2010 (November): Selected for Oral presentation at RECOMB/DREAM 2010 for the Systems Biology conference. Title of presentation: "Identification and Analysis of tissue-specific co-expression networks from human samples". (G. Gambardella and D. di Bernardo).

    2010 (July): Selected with fellowship for the PASCAL (Pattern Analysis, Statistical modelling and ComputAtional Learning) bootcamp in Marseille (5-13 July) .

    2009 (September): I attended EMBO course “Networks in biology analysis, modeling and reverse engineering” (21-24 September, Bologna) organized by Giovanni Romeo.



    [1] R. De Cegli, S. Iacobacci, G. Flore, G. Gambardella et al. - Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation - Nucl. Acids Res. (2013) 41(2): 711-726, first published online November 23, 2012; doi:10.1093/nar/gks1136. PDF

    [2] G. Gambardella*, R. Pagliarini*, F. Gregoretti, G. Oliva, and D. di Bernardo - Differential Equation based reverse-engineering algorithms: pros and cons - Springer book (2013) (in press).

    [3] G.Gambardella, M. N. Moretti, R. De Cegli, L. Cardone, A. Peron and D. di Bernardo - Differential Network Analysis for the identification of condition-specific pathway activity and regulation – Bioinformatics (2013).  PDF